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Thrombosis Information - DVT

Prevention Of Perioperative Deep Venous

B. Todd Sitzman, M.D., M.P.H. B. Todd Sitzman, M.D., M.P.H. is with the Department of Anesthesiology and Pain Management, Mayo Clinic Jacksonville. Jacksonville Medicine / December, 1998

What Is Deep Vein Thrombosis?

Deep vein thrombosis (throm-BO-sis) is a blood clot that forms in a vein deep in the body. Most deep vein clots occur in the lower leg or thigh. They also can occur in other parts of the body. January 2006

Exclusion of deep venous thrombosis with D-dimer testing--comparison of 13 D-dimer methods in 99 outpatients suspected of deep venous thrombosis using venography as reference standard.

Thromb Haemost. 2000 Feb;83(2):191-8. Comment in: Thromb Haemost. 2000 Dec;84(6):1134-5. Thromb Haemost. 2000 Feb;83(2):180-1.

How I treat venous thrombosis in children

Blood, 1 January 2006, Vol. 107, No. 1, pp. 21-29.


Mark H. Meissner, MD, and E. Eugene Strandness, Jr., MD

Initial Treatment of Venous Thromboembolism

The objectives of treatment for patients with venous thromboembolism (VTE) (deep venous thrombosis and/or pulmonary embolism) are 1) to prevent death from pulmonary embolism, 2) to relieve symptoms and prevent extension of deep venous thrombosis, 3) to prevent recurrent VTE, and 4) to prevent the post thrombotic syndrome. The anticoagulant drugs heparin, low molecular weight heparin (LMWH) and warfarin constitute the mainstay of treatment of VTE. In selected cases the use of thrombolytic agents and/or the insertion of an inferior vena cava filter may be indicated. The use of graduated compression stockings following an episode of deep venous thrombosis has been shown to decrease the incidence of the post thrombotic syndrome. For further information on the use of heparin and warfarin, please refer to the guidelines located elsewhere on the TIG web site.

Patient information: Venous thrombosis

Gregory YH Lip, MD, FRCPE, FESC, FACC The University of Birmingham Graham F Pineo, MD Foothills Hospital Kenneth A Bauer, MD Harvard Medical School

Deep Venous Thrombosis and Thrombophlebitis

Last Updated: March 2, 2005

Deep Venous Thrombosis

Another article by Craig Freied, MD from emedicine site

DVT diagnosis failure criticised

Hospitals are failing to properly diagnose patients with potentially fatal deep vein thrombosis, according to a public service watchdog. Published: 2006/05/31 18:28:41 GMT © BBC MMVI

Post Graduate Medicine DVT

Here is a list of terms useful to the new DVT patient

Flight-related Deep Vein Thrombosis (DVT) -Economy Class Syndrome

(posted 7/1/01)

Deep venous thrombosis

Update Date: 10/28/2003 Updated by: Ezra E. W. Cohen, M.D., Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL. Review provided by VeriMed Healthcare Network.

Does acute infection raise the risk of venous thromboembolism?

Smeeth L, Cook C, Thomas S, Hall AJ, Hubbard R, Vallance P. Risk of deep vein thrombosis and pulmonary embolism after acute infection in a community setting. Lancet. APRIL1–7 2006;367:1075-1079. Answer: Yes. Acute urinary or respiratory tract infection is linked to a substantial but reversible increase in the risk of venous thromboembolism. The risk increased significantly in the first 2 weeks after acute infection and gradually returned to baseline over 12 months.

Is Heparin or LMWH Safer and More Efficacious for Initial Treatment of VTE? Is It Cost-Effective or Cost-Saving To Use LMWH rather than Unfractionated Heparin for the Initial Treatment of VTE?

Ann Fam Med. 2007;5(1):74-80. ©2007 Annals of Family Medicine, Inc.

Coalition to Prevent DVT

DVT occurs when a blood clot forms in a deep vein, usually in the lower limbs. A complication of DVT, pulmonary embolism, can occur when a fragment of a blood clot breaks loose from the wall of the vein and migrates to the lungs, where it blocks a pulmonary artery or one of its branches.


Mayo Clinic January 31, 2005

Reporting Standards for Endovascular Treatment of Lower Extremity Deep Vein Thrombosis

Vedantham et al. 17 (3) 417

DVT victims denied right to sue

Victims of deep vein thrombosis have lost their appeal for the right to claim compensation from airlines. Last Updated: Thursday, 8 December 2005, 13:02 GMT

Anticoagulation for three versus six months in patients with deep vein thrombosis or pulmonary embolism, or both: randomised trial

BMJ, doi:10.1136/bmj.39098.583356.55 (published 8 February 2007) Conclusion: For patients in the UK with deep vein thrombosis or pulmonary embolism and no known risk factors for recurrence, there seems to be little, if any, advantage in increasing the duration of anticoagulation from three to six months. Any possible advantage would be small and would need to be judged against the increased risk of haemorrhage associated with the longer duration of treatment with warfarin.

Deep Venous Thrombosis, Lower Extremity

Another article from emedicine site, radiological perspective

Laboratory Markers in the Diagnosis of Venous Thromboembolism

(Circulation. 2004;109:I-4 – I-8.) © 2004 American Heart Association, Inc.

Diagnosis and treatment of deep-vein thrombosis

CMAJ • October 24, 2006; 175 (9). doi:10.1503/cmaj.060366. © 2006 CMA Media Inc. or its licensors. Deep-vein thrombosis (DVT) is a common condition that can lead to complications such as postphlebitic syndrome, pulmonary embolism and death. The approach to the diagnosis of DVT has evolved over the years. Currently an algorithm strategy combining pretest probability, D-dimer testing and compression ultrasound imaging allows for safe and convenient investigation of suspected lower-extremity thrombosis. Patients with low pretest probability and a negative D-dimer test result can have proximal DVT excluded without the need for diagnostic imaging. The mainstay of treatment of DVT is anticoagulation therapy, whereas interventions such as thrombolysis and placement of inferior vena cava filters are reserved for special situations. The use of low-molecular-weight heparin allows for outpatient management of most patients with DVT. The duration of anticoagulation therapy depends on whether the primary event was idiopathic or secondary to a transient risk factor. More research is required to optimally define the factors that predict an increased risk of recurrent DVT to determine which patients can benefit from extended anticoagulant therapy.

DVT and Pulmonary Embolism: Part I. Diagnosis

Am Fam Physician 2004;69:2829-36. Copyright© 2004 American Academy of Family Physicians. DINO W. RAMZI, M.D., C.M., and KENNETH V. LEEPER, M.D., Emory University School of Medicine, Atlanta, Georgia

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