APS Foundation of America, Inc. - APS - Cardiology & Pulmonology Related

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APS - Cardiology & Pulmonology Related

Association of antibodies against phospholipids with heart valve disease in systemic lupus erythematosus.

Lancet. 1990 Jun 30;335(8705):1541-4.

Assessment of Cardiac Structure and Left Atrial Appendage Functions in Primary Antiphospholipid Syndrome

Stroke. 2005;36:592. © 2005 American Heart Association, Inc. Conclusions— It was concluded that disease process in PAPS frequently involved cardiac valves especially mitral valve but spared LAA function. LAA function was normal, but intracardiac thrombus was present in 5 patients and 1 of them was located in LAA. MR in PAPS patients seems to impair LAA function.

Libman-sacks endocarditis and primary antiphospholipid syndrome.

J Heart Valve Dis. 2005 Sep;14(5):700-2. Cardiac involvement is a not uncommon complication in patients with antiphospholipid syndrome (APS). Herein, the case is reported of cardiac failure in a female patient with Libman-Sacks endocarditis and with primary APS diagnosed eight years previously. Aggressive anticoagulation therapy and medical treatment for the cardiac failure over a 12-month period resulted in a partial regression of the severe mitral regurgitation. Close clinical and echocardiographic surveillance during the follow up of patients with APS and heart valve disease is mandatory. Optimal treatment, including adequate aggressive anticoagulation therapy and specific treatment for heart failure, may play a pivotal role in reducing the severity of valve dysfunction in these patients.

Antiphospholipid syndrome presenting as cardiac failure

Q J Med 2001; 94: 504-506

Antiphospholipid syndrome and vascular disease

Cas Lek Cesk. 1999 Apr 26;138(9):276-9.

Antiphospholipid antibody syndrome as the cause of clinical rapidly progressing vasculopathy

Dtsch Med Wochenschr. 2000 May 12;125(19):589-93.

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