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*APSFA's Favorites    *In the News - APSFA    APS - *General    APS - Cardiology & Pulmonology Related    APS - Catastrophic Antiphospholipid Syndrome    APS - Hematology & Rheumatology Related    APS - Lupus Related    APS - Lupus Research & Trials Information    APS - Nephrology Related    APS - Neurology Related    APS - Opthalmology Related    APS - Other    APS - Pregnancy    APS - Seronegative APS - SNAPS    APS Support Groups & Chat    Autoimmune Diseases - Other    Cardiology & Pulmonology Related Information    Disability Resources    Doctor Information    General Information    Genetic Clotting Problems    INR & INR Machines    Loss Information    Lupus Information - General    Lupus Information - Journal Articles    Medic Alert Information    Medication Information - *General    Medication Information - *Prescription Assistance    Medication Information - Anticoagulants    Medication Information - Antiplatelets    Medication Information - Antithrombotics    Medication Information - Herbals    Medication Information - Other    Migraine & Headache Information    No Clots but Test Positive    Other Medical Problems    Pain & Pain Management    Personal Medical Stories    Pregnancy Information    Professional Medical Websites    Stroke & TIA Information    Supports INR Greater Than 3    Thrombosis Information - *General    Thrombosis Information - DVT    Thrombosis Information - Other    Thrombosis Information - PE   

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Doctor Information

 
*APS Doctor List - *USA  
compiled by the APS Foundation of America, Inc. The APSFA does not endorse any of these doctors, they were simply suggested to us by others. Please be sure to call the office to ensure that the doctor will take your health insurance and is accepting new patients.
 
*APS Doctor List - Canada  
compiled by the APS Foundation of America, Inc. The APSFA does not endorse any of these doctors, they were simply suggested to us by others. Please be sure to call the office to ensure that the doctor will take your health insurance and is accepting new patients.
 
*APS Doctor List - Other Countries  
compiled by the APS Foundation of America, Inc. The APSFA does not endorse any of these doctors, they were simply suggested to us by others. Please be sure to call the office to ensure that the doctor will take your health insurance and is accepting new patients.
 
*APS Doctor List - UK  
compiled by the APS Foundation of America, Inc. The APSFA does not endorse any of these doctors, they were simply suggested to us by others. Please be sure to call the office to ensure that the doctor will take your health insurance and is accepting new patients.
 
ACAM Find A Doctor  
This database lists members on record of the American College for Advancement in Medicine. Listing in this database does not constitute a recommendation by ACAM or the APSFA.
 
Agency for Healthcare Research and Quality  
Tips on choosing a quality health provider, check out this guide.
 
Antiphospholipid Antibodies by Sr. Stephan Moll (Q/A)  
Q:"I've been diagnosed with anticardiolipin antibody syndrome. I'm also a prothrombin 20210A heterozygote, and have elevated homocysteine levels. Following several clots and a stroke, my local health care providers are interested in getting me seen by folks with more expertise/experience. Can you recommend where we might turn?Is there an anticardiolipin expert here in the US? Is there a center doing research or clinical trials in which I might participate?"
 
Boston Hemophilia Center Staff Directory  
 
Consumers' Checkbook  
A nonprofit organization founded in 1974 with the help of funding from the U.S. Office of Consumer Affairs, that publishes market data on physicians, hospitals and health plans.
 
DoctorDirectory.com  
Since 1996, DoctorDirectory.com has been the leading independent online directory for finding a doctor by specialty. Every year there are approximately 900 million physician and patient appointments in the United States. Over 100 million of those annual physician and patient appointments are first time appointments, and over 60 million of those happen without a referral from another physician or health plan. DoctorDirectory.com is a free service to doctors and other medical professionals and their prospective patients. DoctorDirectory.com provides physicians with the following; 1) patients, 2) cash for research, 3) online samples, 4) practice management advice, and 5) many other services to help their practice be successful. DoctorDirectory.com serves the world’s leading pharmaceutical prescription drug manufacturing companies with the following interactive Rx brand marketing solutions; Market Research, eSampling (online samples), eDetailing (online details), physician and patient messaging and online advertising targeted by ailment or specialty.
 
DoctorFinder through the American Medical Association  
DoctorFinder provides you with basic professional information on virtually every licensed physician in the United States. This includes more than 690,000 doctors. AMA member physicians are offered an expanded listing that contains additional information such as office hours, accepted insurance providers, educational history and other helpful information.
 
Find a Doctor on Book of Doctors - Ratings Reviews Free Doctor Listings Directory  
Read what patients have to say about them on Book of Doctors. Find a doctor in any speciality through our doctor directory and read detailed patient reviews and ratings. Our doctor listings provide as much information as possible to new patients before they make their important health decision. Along with detailed office information (hours, insurance plans, medicare, education, certifications, etc.), visitors can find reviews, recommendations or ratings about each doctor and submit new ratings as well. Book of Doctors directory contains thousands of doctors and growing daily so check back again if you don't find a doctor that meets your needs. Please visit our sponsors to help support our free directory (Watch Pavilion & Healio Health)
 
Find a doctor using Yahoo  
Search by location, specialty, name, insurance, or hospital
 
Find a Hematologist  
Find a Hematologist is a new service offered by the American Society of Hematology (ASH) for both patients looking for hematologists in their community and medical professionals who want to make referrals. Users can search by name, location, specialty, or clinical interest, and will be provided with contact information for hematologists meeting the search criteria.
 
Find a Provider  
The Centers for Disease Control and Prevention supports a network of specialized health-care centers to prevent and reduce complications experienced by persons with certain hereditary blood disorders.
 
Find your Doctor. Know your Doctor.  
 
Geographic Membership Directory from the American College of Rheumatology  
This compilation a proprietary product of the American College of Rheumatology. The contents of our online directory may not, in whole or in part, be reproduced, copied, disseminated, entered into a computer database, or otherwise utilized, in any form or manner or by any means, except for the user’s individual, personal and confidential reference. You do not have permission to make any copies of these lists or to contact more than one doctor at a time via mass mailings, e-mail or fax broadcasting, or telephone solicitation. Mailing lists are available from the ACR for one-time use for purposes conducive to our mission.
 
Health Pages (Find a Doctor)  
Health Pages is an online consumer health care service. We publish reader-friendly information on general health care topics and community-specific comparative information on physicians, hospitals, allied health professionals and health plans. Consumers can search our national database of over 500,000 physicians and compare doctors in any specialty according to their experience, hospital affiliations, office services and fees. Health Pages also incorporates the provider directories of over 300 managed care plans into our physician superdirectory, which allows consumers to determine what plans each doctor is affiliated with. The library of articles on such topics as prostate cancer, managed care, Medigap insurance policies, weight loss centers or maternity care are applicable nationwide. What differs from city to city is the comparative provider information.
 
HealthGrades  
A publicly traded company that rates hospitals, physicians and nursing homes, offers a free, searchable database that allows consumers to see how hospitals stack up.
 
Hospital Compare  
This tool provides you with information on how well the hospitals in your area care for all their adult patients with certain medical conditions. This information will help you compare the quality of care hospitals provide. Hospital Compare was created through the efforts of the Centers for Medicare and Medicaid Services (CMS) and organizations that represent hospitals, doctors, employers, accrediting organizations, other Federal agencies and the public. Talk to your doctor about this information to help you, your family and your friends make your best hospital care decisions.
 
Joint Commission on Accreditation of Healthcare Organizations  
Consumers can use to compare hospitals on quality and safety measures.
 
NIH Pediatric Rheumatology Clinic  
The NIH Pediatric Rheumatology Clinic is located at: The National Institutes of Health Warren Grant Magnuson Clinical Center 9000 Rockville Pike 10 Center Drive Building 10, Outpatient 13 Bethesda, MD 20892
 
Physician Credentials: How Can I Check Them?  
 
RateMDs.com - Doctor Ratings and Reviews  
RateMDs.com allows patients to rate and read about their doctors and dentists. This is a fairly new website, so please add your doctors and rate them!
 
Recommended Doctors  
 
Second opinion counts for a lot  
© Copyright 2006 USA TODAY
 
Sites for Checking Health-Related Credentials  
This page was revised on January 31, 2005.
 
SMFM Physician Locator  
The Physician Locator tool allows you to search our database for members of the Society for Maternal-Fetal Medicine. Results of the search will be based on the parameters that you enter into the the form below. There is agreement you must accept before using it.
 
Symptom Checker  
What's causing your foot pain? Why does your child's throat hurt? And what should you do about it? Use this guide to discover the most common causes of the most common symptoms.
 
WebMD Physician Directory  
The WebMD Physician Directory is compiled and regularly updated by The Little Blue BookTM, a WebMD company. What's more, all information in the directory is confirmed directly with the source -- the doctors themselves. The award-winning Little Blue Book is well-known in the medical industry for its accurate, up-to-date physician information.
 
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General Information

 
*APS Foundation of America, Inc Cafe Press Gear  
100% of the profits from these products will go to the APS Foundation of America, Inc. APS Stands for Antiphospholipid Antibody Syndrome, which is a blood disorder that causes blood clots, strokes in young people and multiple miscarriages in women. The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner. Thanks for looking! Please see our two other cafe press sites at www.cafepress.com/lupusaps and www.cafepress.com/thrombophilia
 
Acute neurologic symptoms—TIA, migraine, or something else?  
What diagnostic studies need your immediate attention? What is the patient's short-term stroke risk? These experts outline a rational approach to this often underestimated emergency.
 
American Autoimmune Related Diseases Association  
The American Autoimmune Related Diseases Association is dedicated to the eradication of autoimmune diseases and the alleviation of suffering and the socioeconomic impact of autoimmunity through fostering and facilitating collaboration in the areas of education, research, and patient services in an effective, ethical and efficient manner.
 
American Society of Hematology Patient Resources  
ASH provides a wide variety of information and resources for patients with blood disorders, such as links to patient support groups, free access to Hematology (containing current disease-specific information), and a Find a Hematologist feature to help match patients with practicing hematologists in their area.
 
Anxiety and Panic: Getting Control over Your Feelings  
Anxiety can be a normal "alarm system" alerting you to danger. Your heart beats fast. Your palms get sweaty. Your mind races. Sometimes anxiety can give you energy to get things done. But anxiety can get out of control and make you feel afraid for no reason. Copyright © 2006 American Academy of Family Physicians.
 
Blood & Marrow Transplant Information Network (BMT InfoNet)  
Blood & Marrow Transplant Information Network (BMT InfoNet) is working with staff at the National Cancer Institute to identify the greatest challenges facing patients who have, or have had, chronic graft-versus-host disease (GVHD).
 
Caring for a painful venous leg ulcer  
Hanne Vogensen presents a case study which outlines the care of a Danish leg ulcer patient. Hanne Vogensen, RN is a Tissue Viability Specialist, Bispebjerg Hospital, Copenhagen, Denmark. Article accepted for publication: June 2006
 
Choices You Must Make to Live Successfully with Chronic Illness  
Written by: Lisa Copen
 
Deciphering Medspeak  
Like millions of Americans, you have probably read a newspaper or magazine article, tuned into a radio or television program, or searched the Internet to find answers to health questions. If so, you have probably encountered "medspeak," the specialized language of health professionals. The Medical Library Association has developed "Deciphering Medspeak" to help you translate common "medspeak" terms. You'll also find some tips on how to identify quality health care information on the Internet.
 
Depression: What You Should Know  
When doctors talk about depression, they mean the medical illness called major depression. Someone with major depression has symptoms like those listed in the box below nearly every day, all day, for two weeks or longer. If you're depressed, you may also have headaches, other aches and pains, stomach problems, and problems with sex. An older person with depression may feel confused or have trouble understanding simple requests. Copyright © 2006 American Academy of Family Physicians.
 
Does your doctor's lingo have you in a tizzy?  
By Dr. Judith Reichman “Today” show contributor Updated: 1:08 p.m. ET Sept. 20, 2005
 
Emotional Health: What You Should Know  
People with good emotional health are in control of their thoughts, feelings, and the way they act. They feel good about themselves and have good relationships. They can keep problems under control. It's important to remember that even people with good emotional health can sometimes have emotional problems or mental illness. But people with good emotional health have learned how to cope with stress and problems. Copyright © 2006 American Academy of Family Physicians.
 
End-of-Life Choices and Compassion In Dying  
Compassion & Choices maintains the mission of improving care and choices at the end of life. Our combined strength ideally positions us to make the greatest strides yet in our quest.
 
Frantic patients, lonely decisions on treatment  
The New York Times, MONDAY, AUGUST 15, 2005
 
HealingWell.com  
Articles, news, information, video webcasts, message forums and chat rooms, email, books, resource directory and more.
 
healthfinder® - your guide to reliable health information  
healthfinder® is an award-winning Federal Web site for consumers, developed by the U.S. Department of Health and Human Services together with other Federal agencies. Since 1997, healthfinder® has been recognized as a key resource for finding the best government and nonprofit health and human services information on the Internet. healthfinder® links to carefully selected information and Web sites from over 1,500 health-related organizations.
 
How To Protect Yourself Against Lyme Disease  
Lyme disease is the most common tick-borne disorder in the United States. Lyme disease can affect the joints, nervous system, heart, skin, and eyes.
 
Influenza Symptoms, Protection, and What to Do If You Get Sick  
Page last modified January 14, 2006
 
Is Your Problem Brain Fog or Alzheimer's Disease?  
 
MedlinePlus  
MedlinePlus will direct you to information to help answer health questions. MedlinePlus brings together authoritative information from NLM, the National Institutes of Health (NIH), and other government agencies and health-related organizations. Preformulated MEDLINE searches are included in MedlinePlus and give easy access to medical journal articles. MedlinePlus also has extensive information about drugs, an illustrated medical encyclopedia, interactive patient tutorials, and latest health news.
 
MedSpeak Glossary of Terms  
Click on MedSpeak. The Medical Library Association has developed "Deciphering Medspeak" to help you translate common "medspeak" terms. You'll also find some tips on how to identify quality health care information on the Internet.
 
National Bone Marrow Transplant Link  
The nbmtLink is a non-profit organization specifically serving stem cell transplant (SCT) patients, their caregivers, families, and health professionals. In 1992, the nbmtLink was founded by those who had experienced the gap in information and support services for SCT patients and were inspired to establish an organization dedicated to meet these needs.
 
National Center for Health Statistics  
Welcome to the National Center for Health Statistics' Web site, a rich source of information about America’s health. As the Nation’s principal health statistics agency, we compile statistical information to guide actions and policies to improve the health of our people. We are a unique public resource for health information–-a critical element of public health and health policy.
 
National Women's Health Resource Center (NWHRC)  
The not-for-profit National Women's Health Resource Center (NWHRC) is the leading independent health information source for women. NWHRC develops and distributes up-to-date and objective women's health information based on the latest advances in medical research and practice.
 
Next Steps After Your Diagnosis: Finding Information and Support  
Next Steps After Your Diagnosis offers general advice for people with almost any disease or condition. And it has tips to help you learn more about your specific problem and how it can be treated.
 
Oh, by the way...why am I losing my hair?  
May 1, 2006. By: Sharon T. Phelan, MD. Contemporary OB/GYN Registration Required
 
Quick Tips—When Getting Medical Tests  
AHRQ Publication No. 01-0040b, May 2002. Agency for Healthcare Research and Quality, Rockville, MD.
 
Quick Tips—When Talking with Your Doctor  
AHRQ Publication No. 01-0040a, May 2002. Agency for Healthcare Research and Quality, Rockville, MD.
 
Redefining Self Care  
Written by: Roz Laraway, MS Clinical Therapist, Franciscan Skemp Healthcare “Here’s the deal. You are made up of a body, a mind, and a spirit. When any one of these is in turmoil, it affects the others.”
 
Search for and Buy APS Books on Amazon.com  
Search and Buy Books about APS on Amazon.com
 
Stress: How to Cope with Life's Challenges  
Stress is caused by the body's instinct to defend itself. This instinct is good to have in emergencies, such as getting out of the way of a speeding car. But it can cause physical problems if it goes on for too long. When you have stress caused by life's daily challenges, your body has to work overtime, with no place to put all the extra energy. This can make you feel anxious, afraid, worried, and uptight. Copyright © 2006 American Academy of Family Physicians.
 
Striving for Quality Advance Care Planning  
written by Linda Briggs, RN, MS, MA Associate Director Respecting Choices and Ethics Consultant
 
The importance of health literacy  
Millions of people in the US are unable to adequately understand basic health information, and the consequences can be grave
 
The MAGIC Foundation  
The MAGIC Foundation is a national non-profit organization created to provide support services for the families of children afflicted with a wide variety of chronic and/or critical disorders, syndromes and diseases that affect a child’s growth. Since its inception the Foundation has grown to include support services for adults who were also impacted by these disorders.
 
The World's Healthiest Foods List, A-Z  
© 2002-2005 The George Mateljan Foundation
 
US Health and Human Services  
 
ValleyRally.com  
Valley Rally.com is a site that focuses on achieving success. The inspirational stories of success posted by our members will help give you the motivation and confidence to overcome similar struggles in your life.
 
Vascular Disease Foundation  
Established in 1998 the Vascular Disease Foundation (VDF) is the only multidisciplinary national public 501(c)(3) non-profit organization focused on vascular diseases with the sole purpose of providing public education and improving awareness about vascular diseases. The mission of the VDF is to reduce death and disability from vascular diseases and improve vascular health for all Americans.
 
Venous Access Port Problems  
Last Updated: July 15, 2001
 
WedMD  
 
Welcome to Precision BioLogic  
In the coagulation lab, you want confidence in the results you are reporting. You want to do things quickly and get it right the first time.
 
Welcome to Your Support Hosiery Superstore!  
Information on Support Hose also has some links to articles related to DVT and pulmonary embolisms.
 
Women's Conditions Health Center  
Women's health is an increasingly important field of medicine. Here you'll find in-depth articles on women's health issues such as chronic pelvic pain, fibroids, menstrual problems, and menopause.
 
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Genetic Clotting Problems

 
*Factor V Leiden  
This website is run by a patient who has Factor V Leiden (FVL). This support site has information on FVL and other hypercoagulable conditions, but it is worth noting that not all of the information presented comes from healthcare professionals and not all information is cited. The APSFA does not have any control over the content of the FVL website and cannot confirm that all information provided by it is accurate.
 
Activated protein C resistance  
This page was last modified 13:18, 16 August 2006.
 
Activated Protein C Resistance and Factor V Leiden: A Review  
Archives of Pathology and Laboratory Medicine: Vol. 131, No. 6, pp. 866–871.
 
American College of Medical Genetics Consensus Statement on Factor V Leiden Mutation Testing  
Wayne W. Grody, MD, PhD1, John H. Griffin, PhD2, Annette K. Taylor, MS, PhD3, Bruce R. Korf, MD, PhD4, and John A. Heit, MD5 (ACMG Factor V Leiden Working Group) © 2001-2005 American College of Medical Genetics. All rights reserved
 
Antithrombin III Deficiency  
Antithrombin-III deficiency can cause or lead to thrombosis, a clot forming in a blood vessel. If a clot attached to a blood vessel wall breaks loose and travels in the bloodstream, it is called an embolus. An embolus that reaches a blood vessel in the lungs is called a pulmonary embolism. This type of clot can block the blood vessel, cut off the oxygen supply to the lung tissue, and, in some cases, cause death. Article Reviewed: 1999-03-17
 
Congenital antithrombin III deficiency  
Update Date: 10/28/2003 Updated by: Ezra E. W. Cohen, M.D., Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL. Review provided by VeriMed Healthcare Network.
 
Congenital protein C or S deficiency  
These inherited disorders of blood coagulation are caused by deficiency of the Vitamin K-dependent plasma proteins C or S that are naturally occurring anticoagulants. The disorder results in an increased tendency for intravascular blood clot formation. Update Date: 4/15/2005 Updated by: Rita Nanda, MD, Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL. Review provided by VeriMed Healthcare Network.
 
Current approaches to the work-up of hypercoagulability:Prothrombin 20210  
Information on Factor II G to A (guainine-to-adenine) gene mutation/genetic predispositions to thrombosis associated with mutation in the prothrombin gene.
 
Excess Factor VIII: A Common Cause of Hypercoagulability  
Abstract Background: Elevations of coagulation factor VIII have recently been described in significant numbers of patients with venous thromboembolism (VTE) previously thought to have had an "idiopathic" event. Three patients from a family practice are presented with recurrent VTE and increased factor VIII levels. Method: The case histories and results of laboratory tests were reviewed. Results: The 3 patients had no other clear coagulopathy. In 2 of the 3, the increase was confirmed with a second reading. Conclusions: Factor VIII assay should be considered in the work-up of idiopathic, recurrent VTE. Long-term anticoagulation may be appropriate in this setting.
 
Factor V deficiency  
Factor V deficiency is an inherited abnormal blood coagulation disorder caused by a deficiency of the plasma protein Factor V.
 
Factor V Leiden  
Factor V Leiden (sometimes Factor VLeiden) is a hypercoagulability disorder in which Factor V, one of the coagulation factors, cannot be deactivated. Factor V Leiden is the most common hereditary hypercoagulability clotting disorder amongst Eurasians, possibly affecting up to 5% of the population of the U.S. It is named after the city Leiden (The Netherlands), where it was first identified in 1994 by Prof R. Bertina et al.
 
Factor V Leiden - Cardiology Patient Page  
Circulation 2003; 107:e94-97. (c) 2003 American Heart Association, Inc.
 
Factor V Leiden and Antiphospholipid Antibodies Are Significant Risk Factors for Ischemic Stroke in Children  
(Stroke. 2000;31:1283.) © 2000 American Heart Association, Inc.
 
Factor V Leiden and Pregnancy Issues Support Board  
This list is for people who have Factor V Leiden or similar disorder (such as Inherited or Pregnancy Acquired Thrombophilia) and are trying to get pregnant, already are pregnant, or have been pregnant. Affected partners/family members are also welcome. Within this group, it is not uncommon to have experienced a pregnancy loss, so members are expected to be sensitive to the serious nature of this group. This is a list of support, discussion, and information-sharing. Any challenges or flames will not be tolerated. Please note that new members are automatically moderated to reduce list-spamming. This may cause initial posts to be temporarily delayed in getting sent to the list.
 
Factor V Leiden thrombophilia  
Factor V Leiden thrombophilia is an inherited disorder of blood clotting. Factor V Leiden is the name of a specific mutation that results in thrombophilia, or an increased tendency to form abnormal blood clots in blood vessels. People who have the factor V Leiden mutation are at somewhat higher than average risk for a type of clot that forms in veins, such as the deep veins of the legs (deep venous thrombosis), or a clot that travels through the bloodstream and lodges in the lungs (pulmonary embolism).
 
Factor V Leiden Thrombophilia  
[Hereditary Resistance to Activated Protein C, Factor V Leiden Mutation] Funded by the NIH • Developed at the University of Washington, Seattle
 
Factor V Q506 Mutation (Activated Protein C Resistance) Associated With Reduced Intrapartum Blood Loss - A Possible Evolutionary Selection Mechanism  
 
Factor VII deficiency  
Factor VII deficiency is an inherited disorder that causes abnormal blood clotting (coagulation), resulting from a deficiency of the plasma protein factor VII.
 
Factor X deficiency  
Factor X deficiency is a disorder that causes abnormal blood clotting (coagulation), resulting from a shortage of a plasma protein called factor X.
 
Factor XII (Hageman factor) deficiency  
This is an inherited disorder that causes prolonged clotting (coagulation) of blood in a test tube without a clinical bleeding tendency, and results from a deficiency of the plasma protein factor XII.
 
FDA Approves First Biologic to Treat Rare Clotting Disorder  
The U.S. Food and Drug Administration (FDA) today licensed Ceprotin, the first biologic treatment for patients with a rare genetic defect that can cause a potentially life-threatening clotting disorder. Ceprotin is made from the plasma of healthy human blood donors. It is a concentrated form of Protein C, a substance normally manufactured in the liver that circulates in the plasma in very small amounts. Protein C plays an important role in controlling blood coagulation by preventing the formation and growth of blood clots.
 
Genetic Counseling for Hereditary Thrombophilia  
 
Hereditary Blood Disorders, NCBDDD, CDC  
Hereditary defects in one or more of the clotting factors can cause the formation of potentially dangerous blood clots (thrombosis). Approximately 5-8% of the U.S. population has one of these clotting disorders collectively called thrombophilia, a propensity for blood clotting in which a genetic defect can be identified that often results in thrombosis. More than 60,000 Americans die each year from venous thromboembolism; in addition, nearly half of patients with deep vein clots experience long-term health consequences that adversely affect their quality of life.
 
HIV infection and stroke: if not protein S deficiency then what explains the relationship?  
Journal of Neurology, Neurosurgery, and Psychiatry 2005;76:1331
 
Homocyst(e)ine, Diet, and Cardiovascular Diseases - AHA Science Advisory  
(Circulation. 1999;99:178-182.) © 1999 American Heart Association, Inc.
 
Homocysteine and MTHFR Mutations: Relation to Thrombosis and Coronary Artery Disease  
(Circulation. 2005;111:e289-e293.) © 2005 American Heart Association, Inc. Elizabeth A. Varga, MS; Amy C. Sturm, MS; Caron P. Misita, PharmD; Stephan Moll, MD
 
Molecular Genetics of Blood Clotting  
Summary: David Ginsburg is interested in understanding the components of the blood-clotting system and how disturbances in their function lead to human bleeding and blood-clotting disorders.
 
Protein C Deficiency  
Protein C deficiency is a genetic trait that predisposes one to the formation of venous clots. Protein C deficiency was first described in 1981.
 
Protein C Deficiency : Article by Eleanor S Pollak, MD  
Protein C deficiency, a deficiency of the anticoagulant protein C, is associated with a variably increased risk of thrombosis. In the rare inherited homozygous or compound heterozygous state, protein C deficiency is associated with severe life-threatening neonatal purpura fulminans or massive venous thrombosis. The inherited heterozygous state of protein C deficiency most frequently is associated with deep venous thrombosis of the lower limb but also may manifest in other venous locations. A significant percentage of patients with protein C deficiency remain asymptomatic. A family history is essential in assessing the association of a patient's deficiency with the patient's risk of thrombotic disease. Acquired protein C deficiency occurs in certain clinical scenarios, but this most often is associated with a transient predisposing factor. Last Updated: June 30, 2006
 
Protein S Deficiency And Thrombophilia  
Welcome to our web site. Protein S Deficiency (PSD) is a rare blood disorder that affects just a few thousand people worldwide. It is one of several known risk factors for thrombophilia and can increase the risk of blood clots such as Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE).
 
Protein S Deficiency And Thrombophilia Chat Room (UK)  
 
Protein S deficiency in HIV associated ischaemic stroke: an epiphenomenon of HIV infection  
Journal of Neurology, Neurosurgery, and Psychiatry 2005;76:1455-1456
 
Prothrombin 20210  
Prothrombin is one of the blood clotting factors. It circulates in the blood and when activated, is converted to thrombin. Thrombin causes fibrinogen, another clotting factor, to convert to fibrin strands, which make up part of a clot.
 
Prothrombin 20210 Mutation (Factor II Mutation):Cardiology Patient Page  
(Circulation. 2004;110:e15-e18.) © 2004 American Heart Association, Inc. Elizabeth A. Varga, MS; Stephan Moll, MD
 
Rituxan for Treatment of Idopathic Factor VIII Inhibitors  
June 2003 Power Point Presentation
 
Selective IgA Deficiency  
 
Should one routinely screen for lipoprotein(a)?  
JOSEPH P. FROLKIS, MD, PhD Sections of Preventive Cardiology and Preventive Medicine, Department of Preventive Cardiology and Rehabilitation, Cleveland Clinic
 
Strange inheritance patterns  
Last Updated: 2/15/2004
 
The Genetics of FVL, by Jennifer Rosenberg  
Contributions in design from Jennifer Rosenberg.
 
Von Willebrands Disease  
Matt Klimshuk's Homepage
 
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INR & INR Machines

 
*INR Monitoring in Patients with Antiphospholipid Antibodies with Finger Stick INR Machines.  
by: Stephan Moll, MD. A superb way to monitor INRs (International Normalized Ratio) in patients on oral anticoagulants who do NOT have antiphospholipid antibodies (APLA) is though use of “point of care instruments”, where the INR is tested on blood from a finger stick. This method gives fast results and is used by many physicians’ offices and by some patients at home. However, in patients with APLA on oral anticoagulants these instruments may give inaccurate readings.
 
Anticoagulation Forum  
"Recognizing the growing importance and widespread use of antithrombotic therapy for individuals with thromboembolic disorders, the Forum seeks to develop a network of professionals committed to this therapeutic modality in order to exchange information, provide medical education, and pursue scientific investigation, with the ultimate goals of providing professional development and enhancing the quality of medical care."
 
Antiphospholipid Antibody Syndrome (APS) - NO to Home INR Machines!!  
I started this blog to help get the word out that Home INR machines are NOT safe to use for patients with Antiphospholipid Antibody Syndrome. If you have APS, please read! Thanks!
 
CoagCheck Systems  
Literature clearly states that this machine has problems with APS patient and patients with the Lupus Anticoagulant. This is for the CoaguChek, CoaguChekS and CoaguCheckXS. Please call technical support at 800-428-4674 for more information. Those using this machine should be getting vein draw comparisons at least every 6-8 weeks.
 
CoaguChek & CoaguChek S Strip Insert  
Literature clearly states that this machine has problems with APS patient and patients with the Lupus Anticoagulant. This is for the CoaguChek & CoaguChekS. Please call technical support at 800-428-4674 for more information. Those using this machine should be getting vein draw comparisons at least every 6-8 weeks.
 
CoaguChek XS System - Patient Experience  
Registration Required to read story. "I called Roche and expressed my concerns about the reliability of the machine. They told me that at higher INRs (above 4.0) the machine becomes less reliable. They also told me that the machine doesn't work very well for people with Antiphospholipid Antibodies because these same antibodies are on the test strips! She said that especially when someone with APS is having a flare up the machine may not work well due to the high level of antibodies in the blood."
 
CoaguChekXS Strip Insert  
Literature clearly states that this machine has problems with APS patient and patients with the Lupus Anticoagulant. This is for the new CoaguChekXS. Please call technical support at 800-428-4674 for more information. Those using this machine should be getting vein draw comparisons at least every 6-8 weeks.
 
Devices for ambulatory and home monitoring of blood pressure, lipids, coagulation, and weight management, part 2  
Am J Health Syst Pharm.2005; 62: 1894-1903. Kelly L. Scolaro, Pamela L. Stamm and Kimberly Braxton Lloyd Copyright © 2005 by the American Society of Health-System Pharmacists.
 
Factors That Influence INR system Comparisons  
List includes Antiphospholipid Antibodies
 
For those inquiring about HOME INR machines...  
Registration Required to read this patient experience. "You're putting your life into a machine that is KNOWN to be wrong with APS patients...think TWICE...THREE times...FOUR times and Just say NO!"
 
Hemochron Jr. Package Insert  
Literature clearly states that this machine has problems with APS patient and patients with the Lupus Anticoagulant. Those using this machine should be getting vein draw comparisons at least every 6-8 weeks.
 
Home INR Machines and Antiphospholipid Antibodies  
Home INR machines do not give accurate readings in about 1/3 rd of patients with antiphospholipid antibodies who are on warfarin. This is not due to the machine malfunctioning, but likely due to antibodies interfering with the test method of the home INR machines. In one third of patients with antiphospholipid antibodies the INRs read by the home INR machines are unreliable: (a) they either read too high, compared to INRs tested in a laboratory from an i.v. stick (reference 2), or (b) the instruments flash up an error message (reference 1). This inaccuracy is likely caused by the presence of the antiphospholipid antibodies. Since antibody levels can fluctuate over time, the instrument may give accurate readings at times when the antibody levels are low, but inaccurate ones at times when the levels are higher. This is a phenomenon not unique to the Coaguchek® instrument, but is also seen with the ProTime® and the INRatio® instruments (reference 1,2). In patients who do not have antiphospholipid antibodies the home INR machines give reliable readings and are a good way to monitor warfarin therapy (ref. 3). Last Updated: 8/22/06
 
INR  
 
INRatio by Hemosense  
Representatives & Literature clearly states that this machine has problems with APS patient and patients with the Lupus Anticoagulant. Please see: http://www.hemosense.com/docs/5500317_TechBull108_AntiPhospholipid_RevA.pdf Those using this machine should be getting vein draw comparisons at least every 6-8 weeks.
 
INRatio Monitor and Interfering Substances  
Anti-phospholipid antibodies can disrupt the phospholipid in the PT reagent that is necessary for the clotting reaction to occur thus artificially elevating the INR.
 
My Experience with Home INR Machines  
Patient's story on her use of a Home INR Machine and supporting company information.
 
Patient Variables in PT/INR Testing with INRatio  
Technical Bulliten from HemoSense makers of INRatio. Clearly states that APS effects its results.
 
Point-of-care testing of the international normalized ratio in patients with antiphospholipid antibodies.  
SL Perry, GP Samsa, and TL Ortel Thromb Haemost, December 1, 2005; 94(6): 1196-202. Antiphospholipid antibodies can influence the results of clotting tests in a subset of patients, which can be a major obstacle in monitoring warfarin.The aim was to determine if point-of-care testing of the International Normalized Ratio (INR) is influenced by antiphospholipid antibodies. Please note the manufacture of this machine helped fund this study.
 
Protime Machine  
Representatives clearly state that this machine has problems with APS patients and patients with the Lupus Anticoagulant. Waiver for patients with APS must be signed. Those using this machine should be getting vein draw comparisons at least every 6-8 weeks.
 
ProTime Microcoagulation System Package Insert  
Literature clearly states that this machine has problems with APS patient and patients with the Lupus Anticoagulant. Those using this machine should be getting vein draw comparisons at least every 6-8 weeks.
 
Questions and Answers: For Use with CoaguChek® Test Strip Urgent Medical Device Correction (UMDC) 06-266 and Urgent Medical Device Recall (UMDR) 06-267  
11/16/06: CoaguChekS now has a 30% +/- acceptable standard of deviation.
 
Thoratec Receives FDA Warning Letter, Plans Recall (ProTime)  
Thoratec’s International Technidyne Corp. (ITC) division has received an FDA warning letter citing concerns about its quality systems, specifically those related to certain lots of its ProTime System anticoagulation monitoring device.....of incorrect readings of patient blood coagulation levels.
 
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American Child Photographers Charity Guild (ACPCG)  
A non-profit, volunteer based organization of child photographers from all over the country who have come together to form a guild dedicated to children in need and their families.
 
Association for Death Education and Counseling  
ADEC is one of the oldest interdisciplinary organizations